Data Brief

Evo 2 designs diverse mitochondrial genomes

An AI-generated genome has the same number of coding sequences, tRNA, and rRNA genes as human mitochondria; but its designed sequences are highly diverse.

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The Evo 2 40B model was prompted with small portions of human mitochondrial DNA, and generated 250 unique mitochondrial genomes. These genomes were then compared to different organisms using BLASTp.

Chart: Niko McCartySource: Brixi G. et al.Download image