Correlation between levodopa daily equivalent dose (GLP-1RA treated) and adjusted difference in MDS-UPDRS-3 in Parkinson disease clinical trials

Tight correlation between a higher LEDD and the adjusted difference in MDS-UPDRS-3 suggesting that GLP-1RA might enhance dopaminergic symptomatic effects

The adjusted mean difference is in absolute values (negative values have been converted to positive to denote magnitude regardless of the direction of the change)
Chart: Created by Jose-Alberto Palma MD PhDSource: Published Clinical Trial ResultsEmbed Download imageCreated with Datawrapper