This line chart shows the rate per 100,000 for gender-affirming medication among children, divided by male and female at birth, and divided into puberty blockers and hormone medication. Among females, puberty blockers top out at about 20 per 100,000, at 13 years old. Among males, puberty blockers top out at about 15 per 100,000, at 16 years old. Among females, hormone medication starts at age 12 and increases measurably at 15, up to 140 per 100,000 at 17. Among males, hormone medication starts at age 11 and increases in the teenage years but not as much as for females, ending up at about 80 per 100,000 at 17 years old.