In October 2020 at the University of Pennsylvania, ALS patient Todd Legg started getting injections in a trial of a new drug called tofersen. His condition has stabilized since April 2021, as measured by breathing capacity and an overall score of everyday functions such as walking, speaking, and swallowing. He does not know whether he got the drug or a placebo at first, but he and other participants all got the drug after the initial six months.