The Ten Vaccines With The Most Reported Fatalities (after 1 dose 2020-2025)

This table shows the top ten vaccines in the United States with the highest number of reported fatalities after a single dose, based on CDC data from 2020 to 2025. Variants of the COVID-19 vaccines hold the top three spots.

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Bader Law analyzed data using the Vaccine Adverse Event Reporting System (VAERS) which provides data over the years current to 11/28/2025.

Chart: Bader LawSource: CDC WonderCreated with Datawrapper