Top 10 leading causes of death in the U.S. (total number of deaths), by age, January - September 2022
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| 1 | Accidents (1,174) | Accidents (11,338) | Accidents (23,486) | Accidents (23,293) | Cancer (24,948) | Cancer (80,085) | Cancer (131,013) | Heart disease (123,645) | Heart disease (180,040) |
|---|---|---|---|---|---|---|---|---|---|
| 2 | Cancer (576) | Homicide (4,849) | Suicide (6,340) | Heart disease (9,079) | Heart disease (24,946) | Heart disease (65,346) | Heart disease (102,564) | Cancer (119,913) | Cancer (74,819) |
| 3 | Suicide (451) | Suicide (4,547) | Homicide (5,344) | Cancer (8,097) | Accidents (20,864) | COVID-19 (27,740) | COVID-19 (46,945) | COVID-19 (57,100) | COVID-19 (59,620) |
| 4 | Homicide (340) | Cancer (956) | Heart disease (2,884) | Suicide (5,486) | COVID-19 (11,100) | Accidents (21,686) | Chronic respiratory (27,018) | Chronic respiratory (33,264) | Alzheimer disease (55,602) |
| 5 | Congenital (241) | Heart disease (630) | Cancer (2,606) | COVID-19 (4,635) | Liver disease (7,127) | Diabetes (13,761) | Stroke (20,855) | Stroke (32,664) | Stroke (49,120) |
| 6 | COVID-19 (165) | COVID-19 (553) | COVID-19 (2,078) | Liver disease (3,704) | Suicide (5,437) | Chronic respiratory (12,550) | Diabetes (20,621) | Alzheimer disease (25,593) | Chronic respiratory (26,183) |
